Dapoxetine is the first and only drug specifically developed for the treatment of premature ejaculation. For more information on premature ejaculation, please refer to www.controlPE.ph
|What is dapoxetine?||
Dapoxetine is the first and only drug specifically developed for the treatment of premature ejaculation and is now approved in over 50 countries. Based on robust clinical trials involving over 16,000 men worldwide, dapoxetine is proven to be well-tolerated and to significantly improve all measures of premature ejaculation, including control over ejaculation and sexual satisfaction for the couple.1,2
Dapoxetine is available by prescription in 30 mg and 60 mg oral tablets.
|How does dapoxetine work?||Men with premature ejaculation may have decreased levels of serotonin.3
Dapoxetine quickly increases the synaptic levels of serotonin, improving the symptoms of premature ejaculation.4,5
|How do you take dapoxetine?||
Dapoxetine should be taken, on-demand, one to three hours before intercourse with a full glass of water.
Dapoxetine is indicated for men with premature ejaculation aged between 18 to 64 years, and is clinically proven to work effectively on the first dose.1,6 To optimize individual response, dapoxetine should be taken for at least six doses or four weeks.6 Dapoxetine should not be taken more than what is prescribed, and should not be taken more than once every 24 hours.6
|What side effects may be associated with dapoxetine?||
Based on robust clinical trials involving over 16,000 men worldwide, dapoxetine is proven to be well-tolerated.1,2 Side effects due to dapoxetine are usually mild to moderate and are more frequent in the first week of treatment.1,2 Such side effects include nausea, dizziness and headache.1
|Is dapoxetine safe for consumption by all men?||
Dapoxetine is indicated for men with premature ejaculation aged between 18 to 64 years. Dapoxetine is not recommended for those with significant pathological cardiac conditions, including heart failure, conduction abnormalities (e.g. sick sinus syndrome, heart block or atrioventricular conduction abnormalities), significant ischemic and valvular disease, and history of syncope (fainting).6 Men with current or past mental problems (such as depression, mania, bipolar disorder or schizophrenia), or eye disorders (such as raised intraocular pressure or those at risk of angle closure glaucoma) are advised to seek advice from their physicians before starting treatment with dapoxetine.
|What is the recommended dosage for dapoxetine?||
Dapoxetine is effective from the first dose.1 The recommended starting dose of dapoxetine is 30mg within a 24 hour period.6 A careful appraisal of individual benefit-risk of dapoxetine should be performed by the physician after the first four weeks of treatment (or at least after six doses of treatment) to determine whether continuing treatment with dapoxetine is appropriate.6
|How is dapoxetine different from other treatments for premature ejaculation?||
Dapoxetine is the first and only drug specifically developed for premature ejaculation and now approved in over 50 countries. Dapoxetine is proven to be well-tolerated and to significantly improve all measures of premature ejaculation, including control over ejaculation and sexual satisfaction for the couple.1,2
|What is premature ejaculation?||
Men with premature ejaculation have difficulty controlling ejaculation and often ejaculate with little sexual stimulation before or shortly after the penis enters the vagina, which causes bother or distress.7
According to the 2013 Asia-Pacific Sexual Behaviours and Satisfaction Survey8, 32% of men in Asia-Pacific have some form of premature ejaculation as diagnosed using the Premature Ejaculation Diagnostic Tool (PEDT).9
|How is premature ejaculation diagnosed?||
Premature ejaculation can be diagnosed using the Premature Ejaculation Diagnostic Tool (PEDT), a short five-question, psychometrically validated measure to help diagnose premature ejaculation.9 The PEDT is available at www.controlPE.ph. Men who think they may have premature ejaculation should speak to their physician for a thorough examination.
|Does dapoxetine work for men who have not been diagnosed with premature ejaculation?||
Premature ejaculation is the most common sexual dysfunction in men, affecting up to one in three men (31%) in Asia Pacific.10 Premature ejaculation leads to a decrease in sexual satisfaction and overall quality of life for both men and their partners.2,10
If a couple is not satisfied with their sex life, they should find out if premature ejaculation is a contributing factor. By speaking to their physician and taking the PEDT assessment9 (available at www.controlPE.ph) they can discuss the option of dapoxetine as a treatment for premature ejaculation.
- McMahon CG, Althof SE, Kaufman JM, Buvat J, Levine SB, Aquilina JW, et al. Efficacy and safety of dapoxetine for the treatment of premature ejaculation: integrated analysis of results from five phase 3 trials. J Sex Med. 2011;8(2):524–39.
- McCarty EJ, Dinsmore WW. Dapoxetine: an evidence-based review of its effectiveness in treatment of premature ejaculation. Core Evid. 2012;7:1–14.
- Hellstrom, WJG. Emerging treatments for premature ejaculation: focus on dapoxetine. Neuropsychiatr Dis and Treat. 2009;5:37–46.
- Giuliano F and Clément, Pierre. Serotonin and premature ejaculation: from physiology to patient management. Eur Urol. 2006;50(3):454–466.
- Giuliano F. 5-Hydroxytryptamine in premature ejaculation: opportunities for therapeutic intervention. Trends Neurosci. 2007;30(2):79–84.
- Priligy® (dapoxetine). [Summary of Product Characteristics] Oct 2012.
- Wespes E, Amar E, Eardley I, Giuliano F, Hatzichristou D, Hatzimouratidis K, Montorsi F, et al. European Association of Urology: Guidelines on Male Sexual Dysfunction: Erectile dysfunction and premature ejaculation. [Internet] 2013 Mar [cited 2013 Mar 18]. Available from: http://www.uroweb.org/fileadmin/guidelines/2012_Guidelines_large_text_print_total_file.pdf
- 2013 Asia-Pacific Sexual Behaviours and Satisfaction Survey. [Internet] 2013 May. Available from: [INSERT LINK WHEN SG SURVEY REPORT IS UPLOADED ON WEBSITE]
- Symonds T, Perelman MA, Althof S, Giuliano F, Martin M, May K, et al. Development and validation of a premature ejaculation diagnostic tool. Eur Urol. 2007;52(2):565–73 .
- McMahon CG, Lee G, Park JK, Adaikan PG. Premature ejaculation and erectile dysfunction prevalence and attitudes in the Asia-Pacific region. J Sex Med. 2012;9(2):454–65.